Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage

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Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage

Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF) following in vitro fertilization, 16 women diagnosed with RM and seven recent fathers (control) were examined. Sperm were examined pre- and post-densit...

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I-24: Recurrent Implantation Failure

Recurrent implantation failure (RIF) has many definitions, but usually authors consider RIF, the failure to achieve a pregnancy fallowing 2-6 IVF cycles in which more than 10 high grade embryos were transferred to the uterus. There are a lot of causes for RIF but two main causes of that are related to embryo and endometrium. Chromosomal abnormalities, zona hardening and problems in culture medi...

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Re: sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients.

BACKGROUND The aneuploidy rate is higher in poor-quality sperm samples, which also have higher DNA fragmentation index values. The aim of this study was to assess the relationship between sperm DNA fragmentation in samples from infertile men belonging to couples with recurrent miscarriage or implantation failure and the aneuploidy rate in spermatozoa as well as in embryos from patients. METHO...

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Sperm DNA fragmentation abnormalities in men from couples with a history of recurrent miscarriage.

BACKGROUND Previous studies have described an association between sperm with DNA damage and a history of recurrent miscarriage (RM), although it is not clear whether there is benefit in screening for sperm DNA fragmentation and to what extent DNA fragmentation impacts upon RM. AIMS To identify what proportion of couples experiencing RM are affected by DNA fragmentation abnormalities. MATERI...

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Onm-8: Recurrent Implantation Failure in IVF/ICSI Cycle

The success of assisted reproduction, although gradually increasing over the years, is still less than satisfactory. Many couples have benefited from this treatment; many have also been left frustrated following multiple failed attempts (Bulent Urman et al. 2005). Repeated implantation failure (RIF), defined as three or more failed IVF attempts or failure of IVF after cumula- Abstracts of the 5...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2015

ISSN: 1008-682X

DOI: 10.4103/1008-682x.144946